Luminex Webinars

Overcome Biomarker Multiplexing Challenges in Drug Development

Paul Rhyne, PhD
Chief Scientific Officer
Biologic Development Services

In this 25-minute webinar, you’ll learn about:
- The basics of multiplexing plus considerations for the use of planar versus suspension (bead based) arrays
- Overcoming challenges associated with multiplexing including specificity (cross-reactivity), crosstalk, quantitative ranges for optimal sample dilutions, selectivity, and lot-to-lot variability
- Validation tips including how to achieve precision, parallelism, and stability
- What to do if a single analyte fails

Rhyne shares insights from a review article co-authored with 11 colleagues from pharmaceutical companies, clinical research organizations (CRO), and government agencies over two years titled: Recommendations for Use and Fit-for-Purpose Validation of Biomarker Multiplex Ligand Binding Assays in Drug Development.